Australia have cruised to their second straight win at the netball Quad Series, beating South Africa 63-31 at Newcastle's Entertainment Centre on Wednesday to continue their perfect record against the world No.6 side.

The world champion Australians, who last clashed with South Africa in March 2005, have never been defeated by the Proteas in 28 previous meetings and made sure Wednesday was no different.

The Diamonds, who opened the inaugural series with an emphatic 64-40 triumph over England in Adelaide on Sunday, had just as easy a task on Wednesday.

The South Africans suffered the opposite fate - getting trashed by the Kiwis 63-27 in Adelaide for back-to-back defeats.

Diamonds coach Lisa Alexander was able to give all 12 players valuable court time in an attempt to finetune her charges ahead of their match against New Zealand on Sunday, making all five changes at halftime with Chanel Gomes making her Test debut.

Kim Green, who missed the match against England with injury, made her comeback as a second-half substitute.

Australian sharpshooters Catherine Cox (16 from 17 goal attempts) and Susan Pratley (15/16) began the Diamonds' offensive while Erin Bell (7/11) and Caitlin Basset (25/27) picked up where they left off.

The Diamonds, who started slowly against England on Sunday, showed no signs of sluggishness, racing to 16-9 lead after the first quarter.

Cox and Pratley continued their relentless attack while South Africa really struggled to penetrate the Australian defence of Mo'onia Gerrard, Rebecca Bulley and Renae Hallinan in a strong second term to stretch the lead to 31-18 at the main break.

The Diamonds continued their intensity and pace in the third quarter with Basset relentless in attack while Bulley pulled out some spectacular defensive play to restrict the South Africans to just eight points in the term as Australia widened the gap to 45-26 going into the final term.

Basset continued her prolific shooting in the last quarter with a perfect 14 from 14 to further stretch the lead as the Diamonds ran away with a 32-point win.

"Being able to get all 12 out on the court is always a coach's dream and especially having a victory like that," Diamonds coach Alexander said.

"We are completely respectful of the South Africans, we understand that they've improved enormously and it's a credit to them, they pushed us all the way.

"Even though the score doesn't say that, they definitely pushed us.

"But it's a great confidence boost for sure before our match on Sunday."