Geelong have suffered a blow ahead of Friday's round-20 AFL clash with top-eight rivals West Coast in Perth, losing All-Australian midfielder James Kelly with a groin injury.
The sixth-placed Cats named inexperienced trio Jonathan Simpkin, Cameron Guthrie and Jordan Murdoch on Thursday in their 22-man line-up in place of Kelly, Josh Hunt (quad) and Billie Smedts (calf).
Fifth-placed West Coast have been boosted by the return from suspension of skipper Darren Glass while Norm Smith Medallist Andrew Embley and Jacob Brennan have been recalled.
Wingman Embley, 31, is back for his first game since injuring his shoulder in round two.
Collingwood premiership player and two-time All-Australian Alan Didak returns for his first AFL match since injuring a groin muscle in round 11.
The Magpies, who face ladder leaders Sydney at ANZ Stadium on Saturday night, have also regained Chris Tarrant from a back injury while Martin Clarke has been recalled.
Dane Swan (club suspension), Tyson Goldsack (ankle) and Tom Young are out.
The Swans regain Andrejs Everitt for veteran midfielder Jude Bolton (knee).
Hawthorn rested key forward Lance Franklin (hamstring) for a fifth week, recalling ruckman Max Bailey in a squad of 25 for Sunday's Launceston clash with Port Adelaide.
Franklin (51 goals) has slipped to third in the Coleman Medal behind Fremantle's Matthew Pavlich (55) and North Melbourne's Drew Petrie (52).
Port have recalled Troy Chaplin, Jarrad Redden, Nathan Blee, Darren Pfeiffer and David Rodan for the first game under caretaker coach Garry Hocking.
Adelaide regain key forward Kurt Tippett from concussion and David Mackay for Saturday's game against ninth-placed Fremantle at AAMI Stadium.
Forward Jason Porplyzia is out with a shoulder injury and Richard Tambling has been dropped.
The Dockers lose Luke McPharlin to suspension and have recalled Alex Silvagni and Nicholas Suban.
Beau Wilkes returns to St Kilda's side for Saturday's match with Melbourne at the MCG, while the Demons regain Neville Jetta and Jordie McKenzie.
Carlton have regained forward Andrew Walker and midfielder Mitch Robinson from injury.
The Blues made four changes for Saturday night's game against Brisbane at Etihad Stadium, with Rhys O'Keeffe and Matthew Watson also recalled while key defender Michael Jamison is out with a hamstring injury.
The Lions have also made four changes including Matt Maguire who returns for a possible head-to-head duel with Carlton key forward Jarrad Waite.
Gold Coast have made six injury-enforced changes for Saturday's game against fellow strugglers Greater Western Sydney, who will be without Callan Ward (groin), Jonathon Patton (shoulder) and Toby Greene (groin).
Israel Folau is one of six inclusions for the Giants.
Dustin Fletcher, ruckman David Hille and key forward Stewart Crameri are among the inclusions for eighth-placed Essendon in their 25-man squad for Sunday's mini-elimination final against seventh-placed North Melbourne.
North have named midfielder Leigh Adams, who was rested last week after battling shoulder problems.
Brownlow Medallist Adam Cooney (knee) remains on the sidelines for Western Bulldogs who play Richmond on Sunday at the MCG.
Tom Liberatore (club suspension) is one of three players to go out of the side while Lindsay Gilbee and Andrew Hooper are among six inclusions.
The Tigers have recalled Tom Derickx, Brett O'Hanlon and Matt Dea in an extended squad.