Coach Mickey Arthur has implored Australia's inexperienced cricketers to make their mark on English soil before next year's Ashes tour.
The new-look national team has the chance to test themselves in English conditions in the upcoming five-match one-day series starting on June 29 at Lord's.
With questions still hovering over Australia's middle order, the eight-match tour represents a massive opportunity for the likes of wannabe Ashes tourists Peter Forrest, George Bailey and Steve Smith to impress.
The Australian team will be missing the familiar faces of 37-year-olds Ricky Ponting (omitted) and Mike Hussey (family reasons) with the experience of 556 one-day internationals between them.
"It changes the dynamics quite a bit and that is why we are looking for other players to stand up and take over that responsibility," Arthur said.
"Michael and Ricky are not going to be around forever so this gives the guys out here a chance to stake their claims and an opportunity to make their mark and show us they belong."
It is set to be a searching examination against England's formidable pace attack of James Anderson, Stuart Broad, Steven Finn and Tim Bresnan in traditionally seam-friendly conditions.
Forrest, 26, made a strong start to his one-day career in February with a century and two half centuries in his opening four matches before his numbers dropped off in the West Indies.
Likewise, Tasmanian Bailey, 29, has yet to cement his spot in the 50-over side while 24-year-old Smith is looking to re-ignite his international career.
Bailey and Forrest will not be the only ones finding their way on English soil.
The likes of dashing opener David Warner, wicketkeeper Matthew Wade and quicks Pat Cummins and James Pattinson must also soak up the experience before next year's Ashes series.
Australia's captain Michael Clarke said his players had to grab their chances following a 2-2 draw in the five-match one-day series in the Caribbean.
"I think they did that throughout the one-day summer (in Australia) once Ricky was dropped from the team, we managed to go on and win that tri-series for Australia," he said.
"The boys went to West Indies and did a pretty good job in tough conditions, and again it's going to be new for a lot of players to play in English conditions."
Australia will open their 50-over tour of the UK with a match against Leicestershire at Grace Road on Thursday.
The tourists will play Ireland in Belfast on Saturday and Essex at Chelmsford three days later.